3 results for "GABA A R alpha 3 Small Molecules and Peptides" in Products

GABA A R alpha 3 Small Molecules and Peptides

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six ...

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Potent GABAA agonist; also GABAA-ρ partial agonist

Chemical Name: 5-Aminomethyl-3-hydroxyisoxazole
Purity: ≥98%
Potent GABAA agonist; also GABAA-ρ partial agonist
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GABAA agonist

Alternate Names: Gaboxadol
Chemical Name: 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride
Purity: ≥98%
GABAA agonist
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GABAA partial agonist; displays subtype selectivity

Chemical Name: 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine
Purity: ≥98%
GABAA partial agonist; displays subtype selectivity
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