Muscimol

Tocris Bioscience | Catalog # 0289

Potent GABAA agonist; also GABAA-ρ partial agonist
Tocris Bioscience

Key Product Details

Description

Potent GABAA agonist; also GABAA-ρ partial agonist
View all GABA-A Receptor Agonists »

Product Description

Muscimol is a potent GABAA receptor agonist and partial GABAA-ρ receptor agonist. Inhibits memory retention and attenuates airway constriction in vivo.

Product Specifications for Muscimol

Molecular Weight

114.10

Formula

C4H6N2O2

Storage

Store at RT

Purity

≥98%

Chemical Name

5-Aminomethyl-3-hydroxyisoxazole

CAS Number

2763-96-4

PubChem ID

4266

InChI Key

ZJQHPWUVQPJPQT-UHFFFAOYSA-N

SMILES

NCC1=CC(O)=NO1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 11.41 100

Preparing Stock Solutions for Muscimol

The following data is based on the product molecular weight 114.10.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 8.76 mL 43.82 mL 87.64 mL
5 mM 1.75 mL 8.76 mL 17.53 mL
10 mM 0.88 mL 4.38 mL 8.76 mL
50 mM 0.18 mL 0.88 mL 1.75 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 411 publications citing the usage of this product.

Product Documents for Muscimol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Muscimol

For research use only

Related Research Areas

GABA Receptors

Customer Reviews for Muscimol (1)

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  • test
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: Cerebellum
    Verified Customer | Posted 06/21/2023
    Sonication when dissolved.
    Muscimol was in use to find out the relative level of GABA-A receptor activation by beta-alanine. Outside-out membrane patches of neural cells underwent application of beta-alanine and different concentrations of muscimol, as indicated.
    Muscimol 0289

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