2 results for "GABA-A Receptor Inverse Agonists Small Molecules and Peptides" in Products

GABA-A Receptor Inverse Agonists Small Molecules and Peptides

In mammals there are 8 subunit families, some of which have multiple subtpes; 6α, 3β, 3γ, 1δ, 3ρ, 1ε, 1π and 1θ. The majority of endogenous GABAA receptors in the human brain are composed of two α-subunits, two β-subunits and a single γ-subunit. A subclass of GABAA receptors, GABAA-ρ receptors, are homomeric channels formed exclusively from ρ-subunits. These receptors were previously known as GABAC receptors.

All GABAA subunits ...

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α5-selective GABAA inverse agonist

Chemical Name: 6,7-Dihydro-3-[(2-hydroxyethyl)thio]-6,6-dimethyl-1-(2-thiazolyl)-benzo[c]thiophen-4(5H)-one
Purity: ≥98%
α5-selective GABAA inverse agonist
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α5-selective GABAA inverse agonist

Chemical Name: 3-(1,1-Dimethylethyl)-7-(5-methyl-3-isoxazolyl)-2-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-pyrazolo[1,5-d][1,2,4]triazine
Purity: ≥98%
α5-selective GABAA inverse agonist
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