4 results for "Glucagon R/GCGR Small Molecules and Peptides" in Products

Glucagon R/GCGR Small Molecules and Peptides

Glucagon R (GCGR) is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of GCGR is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in GCGR ...

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Negative allosteric modulator of glucagon and GLP-1 receptors

Chemical Name: 4-[[(4-Cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-ylbenzamide
Purity: ≥98%
Negative allosteric modulator of glucagon and GLP-1 receptors
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Endogenous glucagon receptor agonist

Purity: ≥95%
Endogenous glucagon receptor agonist
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Glucagon receptor antagonist

Purity: ≥95%
Glucagon receptor antagonist
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Potent, orally active human glucagon receptor antagonist

Chemical Name: 4-[3-(5-Bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]pyridine
Purity: ≥98%
Potent, orally active human glucagon receptor antagonist
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