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1 result for "Glucagon R/GCGR" in Products
Glucagon R/GCGR Products
Glucagon R (GCGR) is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of GCGR is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in GCGR are a cause of non-insulin-dependent diabetes mellitus.
Negative allosteric modulator of glucagon and GLP-1 receptors
| Chemical Name: | 4-[[(4-Cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-ylbenzamide |
| Purity: | ≥98% |
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