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4 results for "GR/NR3C1" in Products
GR/NR3C1 Products
Glucocorticoid receptor (GR; NR3C1) is a member of the steroid receptor family. GR are expressed in almost all human tissues and organs. GR bind to its sequences as a homodimer. Two different forms, GR-alpha and GR-beta, differing in their C-terminal parts were isolated. GR-alpha is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GR-beta does not bind glucocorticoids.
Anti-inflammatory glucocorticoid
| Chemical Name: | (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione |
| Purity: | ≥98% |
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Adrenal glucocorticoid; immunosuppressant
| Chemical Name: | 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione |
| Purity: | ≥98% |
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Synthetic glucocorticoid; anti-inflammatory and chemopreventive
| Chemical Name: | (11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione |
| Purity: | ≥98% |
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Dexamethasone synthesized to Ancillary Material Grade
| Chemical Name: | (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
| Purity: | ≥98% |
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