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2 results for "HM74A/PUMA-G/GPR109A Small Molecules and Peptides" in Products
HM74A/PUMA-G/GPR109A Small Molecules and Peptides
The low affinity and high affinity receptors for nicotinic acid (niacin) are the inhibitory G-protein coupled receptors HM74/GPR109B and HM74A/GPR109A, respectively. Binding of niacin to HM74A mediates an anti-lipolytic effect observed on adipose tissue. HM74A is also expressed on mouse splenocytes, as niacin and other vitamins can enhance the mitogenic response of lymphocytes.
Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors
| Alternate Names: | AY 25712 |
| Chemical Name: | 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid |
| Purity: | ≥98% |
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Potent and selective GPR109A (HCA2) agonist
| Chemical Name: | (4aR,5aR)-4,4a,5,5a-Tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2]pyrazole-3-carboxylic acid |
| Purity: | ≥98% |
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