Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
Simple Plex 32x4 panel containing Granzyme B, IFN-gamma 3rd Gen, IL-8/CXCL8, and TNF-alpha 2nd Gen with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with CS (cell culture).
Simple Plex 16x4 panel containing IL-1 beta / IL-1F2, IL-6 3rd Gen, IL-8/CXCL8, and TNF-alpha 2nd Gen with sample diluent SD13. Part # starting with ST01 ships in 3-5 days. Sample type indicated with PS (Plasma/Serum).
Simple Plex 32x6 panel containing IL-10 2nd Gen, IL-2, IFN-gamma 3rd Gen, TNF-alpha 2nd Gen, IL-8/CXCL8, and IL-6 3rd Gen with sample diluent SD13, and wash buffer. Part # starting with ST01 ships in 3-5 days. Sample type indicated with PS (Plasma/Serum).
Simple Plex 32x4 panel containing IL-1b,IL-6 3rd gen,IL-8,TNF-a 2nd gen with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).
Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and up to 8 analytes per cartridge.