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3 results for "IRAK1 Small Molecules and Peptides" in Products
IRAK1 Small Molecules and Peptides
IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that help mediate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domai...
IRAK4 and IRAK1 inhibitor
| Chemical Name: | N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide |
| Purity: | ≥98% |
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Interleukin 1 Receptor Associated Kinase 1 (IRAK1) Degrader (PROTAC®)
| Chemical Name: | N-(4-(4-(2-(((S)-1-((2S,4R)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)piperidin-1-yl)-2-methoxyphenyl)-6-(1H-pyrazol-5-yl)picolinamide |
| Purity: | ≥98% |
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Negative control for the IRAK1 degrader JNJ 1013 (Cat. No. 8029)
| Chemical Name: | N-(4-(4-(2-(((S)-1-((2S,4S)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)piperidin-1-yl)-2-methoxyphenyl)-6-(1H-pyrazol-5-yl)picolinamide |
| Purity: | ≥95% |
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