2 results for "KCC2/SLC12A5" in Products

KCC2/SLC12A5 Products

SLC12A5 is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. It can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing of this gene results in two transcript variants encoding different proteins.

Na+/2Cl-/K+ (NKCC) symporter inhibitor

Chemical Name: 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid
Purity: ≥98%
Na+/2Cl-/K+ (NKCC) symporter inhibitor
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Potent and selective KCC2 inhibitor

Chemical Name: N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide
Purity: ≥98%
Potent and selective KCC2 inhibitor
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