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2 results for "Keap1" in Products
Keap1 Products
Keap1 is a member of the Kelch family of proteins. Keap1 contains an N-terminal BTB/POZ domain that mediates homodimerization. When dimerized, six Kelch repeats on the extended C-terminus interact with and inactivate Nrf2, a potent transcriptional activator of detoxifying enzymes, providing a homeostatic brake on oxidative stress activity.
Inhibitor of Keap1- Nrf2 interaction
| Alternate Names: | LH601A |
| Chemical Name: | (1S,2R)-2-[[(1S)-1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]cyclohexanecarboxylic acid |
| Purity: | ≥98% |
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Nrf2 signaling activator
| Chemical Name: | 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole |
| Purity: | ≥98% |
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