3 results for "Klotho beta Proteins and Enzymes" in Products
Klotho beta Proteins and Enzymes
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin...
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | Q86Z14 |
| Applications: | Bioactivity |
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| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | NP_112457 |
| Applications: | Bioactivity |
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| Reactivity: | Cynomolgus Monkey |
| Source: | NS0 |
| Accession #: | EHH53620.1 |
| Applications: | Bioactivity |
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