Kv11.3 Small Molecules and Peptides

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from bothfunctional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heartrate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cellvolume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming(alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encodingdistinct isoforms. (provided by RefSeq)