LDL Receptor Peptides

The low density lipoprotein receptor gene family is a group of endocytic receptors that mediate the uptake of lipoproteins. There are nine LDL receptors in mammals, LDL, VLDL, ApoER2, LRP5, LRP6, MEGF7, LRP1, LRP1B and Megalin, all of which share common structural motifs for receptor-mediated endocytosis. The extracellular domains contain clusters of complement-type repeats and epidermal growth factor precursor domains which are essential for ligand binding and pH-dependent release of ligands ...