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2 results for "LXR-like Receptor Antagonists Small Molecules and Peptides" in Products
LXR-like Receptor Antagonists Small Molecules and Peptides
Liver X receptors (LXRs) and farnesoid X receptors (FXRs) are members of the steroid analog-activated nuclear receptor subfamily, which form heterodimers with members of the retinoid X receptor family. There are two closely related isoforms of each of these enzymes; LXRα and LXRβ, and FXRα and FXRβ (pseudogene in man).
LXRα and FXRα expression is restricted to the liver, small intestine, kidney and adrenal gland, whilst LXRβ and FXRβ are ubiquitously ...
Potent LXR antagonist
| Chemical Name: | 2,4,6-Trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]benzenesulfonamide |
| Purity: | ≥98% |
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Potent FXR antagonist
| Chemical Name: | 1-[(3-Methoxyphenyl)methyl]-N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-3-(4-methylphenyl)-1H-pyrazole-4-carboxamide |
| Purity: | ≥98% |
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