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2 results for "Lysosomal Acid Lipase Inhibitors" in Products
Lysosomal Acid Lipase Inhibitors
Lysosomal acid lipase (LAL) EC 3.1.1.13 is an enzyme responsible for the breakdown of cholesteryl esters and triglycerides in lysosomes and is encoded by the Lipase A, lysosomal acid type (LIPA) gene. LAL plays a key role in lipophagy and mutations in the LIPA gene lead to lysosomal storage disorders.
Following internalization of lipoprotein particles via receptor mediated endocytosis, LAL catalyzes the hydrolysis of cholesteryl esters and triglycerides. This process produces free cholesterol ...
Potent and selective LAL inhibitor
| Chemical Name: | 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate |
| Purity: | ≥98% |
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Selective LAL inhibitor
| Chemical Name: | 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate |
| Purity: | ≥98% |
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