4 results for "mGluR7" in Products

mGluR7 Products

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of ...

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Positive allosteric modulator of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant

Chemical Name: 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Purity: ≥98%
Positive allosteric modulators of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant
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Positive allosteric modulator of group I mGlu receptors

Chemical Name: (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester
Purity: ≥98%
Positive allosteric modulator of group I mGlu receptors
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Selective positive allosteric modulator of group III mGlu receptors

Alternate Names: ML 396
Chemical Name: N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide
Purity: ≥98%
Selective positive allosteric modulator of group III mGlu receptors
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Negative allosteric modulator of mGlu7 receptors; brain penetrant

Chemical Name: 6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone
Purity: ≥98%
Negative allosteric modulator of mGlu7 receptors; brain penetrant
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