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2 results for "Mitochondrial Calcium Uniporter Inhibitors" in Products
Mitochondrial Calcium Uniporter Inhibitors
The mitochondrial Ca2+ uniporter (MCU) is a transmembrane protein that modulates mitochondrial Ca2+ uptake. Sequestration of Ca2+ is important for the processes of oxidative phosphorylation and induction of the mitochondrial permeability transition (MPT).
The MCU is one of the main mechanisms by which mitochondria can take up Ca2+. Ca2+ accumulation via MCU is dependent on the calcium concentration gradient between the cytosol and mitochondrial matrix and the membrane potential (Δψm) ...
Na+/Ca2+ exchange inhibitor (reverse mode)
| Chemical Name: | 2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate |
| Purity: | ≥98% |
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Negative modulator of mitochondrial Ca2+ uniporter (MCU)
| Chemical Name: | 4-[[4-(Diethylamino)phenyl]amino]-6-methyl-3-quinolinecarboxylic acid ethyl ester |
| Purity: | ≥98% |
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