N-Cadherin Proteins and Enzymes

Neuronal Cadherin, also known as Cadherin-2, is a 130 kDa type I membrane protein belonging to the Cadherin superfamily of calcium-dependent adhesion molecules. In the nervous system, N-Cadherin mediates adhesion between the opposing faces of developing neuronal synapses and between Schwann cells and neuronal axons. It interacts in cis or in trans homophilically and with the GluR2 subunit of neuronal AMPA receptors. During synaptic maturation, its expression is lost from inhibitory terminals ...