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2 results for "Nrf2 Inhibitors Small Molecules and Peptides" in Products
Nrf2 Inhibitors Small Molecules and Peptides
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2, also known as NFE2L2) is a member of the basic leucine zipper family of transcription factors. Under normal physiological conditions, Nrf2 has a short half-life of around 20 minutes and is retained in the cytoplasm before being degraded by the concerted actions of Kelch-like ECH-associated protein 1 (Keap1) and Cullin 3. Cullin 3, a ubiquitin E3 ligase ubiquitinates Nrf2, targeting it for proteasomal degradation, in a process facilitated by the ...
| Chemical Name: | N-[4-[2,3-Dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide |
| Purity: | ≥98% |
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| Chemical Name: | 1-[(3R)-3-[3-(4-Amino-1,3,5-triazin-2-yl)-5-chlorophenyl]-4-morpholinyl]-2-propen-1-one |
| Purity: | ≥98% |
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