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3 results for "NTS1/NTSR1 Small Molecules and Peptides" in Products
NTS1/NTSR1 Small Molecules and Peptides
Neurotensin receptor-1 (NTSR1) is a G protein-coupled receptor (GPCR) that has been identified as a mediator of cancer progression. It mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. Defects in NTSR are associated with variance in ...
Selective non-peptide NTS1 antagonist
| Chemical Name: | 2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carboxylic acid |
| Purity: | ≥98% |
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Selective NTS1 partial agonist
| Alternate Names: | ML 301 analog |
| Chemical Name: | N-[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]-L-leucine |
| Purity: | ≥98% |
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Highly potent NTS receptor antagonist
| Chemical Name: | 2-[[[5-(2,6-Dimethoxyphenyl)-1-[4-[[[3-(dimethylamino)propyl]methylamino]carbonyl]-2-(1-methylethyl)phenyl]-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carboxylic acid |
| Purity: | ≥97% |
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