2 results for "NTS1/NTSR1" in Products

NTS1/NTSR1 Products

Neurotensin receptor-1 (NTSR1) is a G protein-coupled receptor (GPCR) that has been identified as a mediator of cancer progression. It mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. Defects in NTSR are associated with variance in working memory performance among healthy adults.

Selective non-peptide NTS1 antagonist

Chemical Name: 2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carboxylic acid
Purity: ≥98%
Selective non-peptide NTS1 antagonist
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Highly potent NTS receptor antagonist

Chemical Name: 2-[[[5-(2,6-Dimethoxyphenyl)-1-[4-[[[3-(dimethylamino)propyl]methylamino]carbonyl]-2-(1-methylethyl)phenyl]-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carboxylic acid
Purity: ≥97%
Highly potent NTS receptor antagonist
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