P2X Receptor Antagonists

P2X Purinergic Receptor Subunits

Each functional P2X receptor is formed from either three identical subunits (homomeric) or a combination of two or three different subunits (heteromeric). Except for P2X₆, all subunits can form homomeric receptors, however, P2X₇ subunits only form homomeric receptors. Functional receptors are named for their constituent subunits, for example a homomeric receptor composed of P2X₇ subunits is called a P2X₇ receptor, while a heteromeric receptor composed of P2X₂ ...