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10 results for "Prokineticin 2" in Products
Prokineticin 2 Products
Prokineticin 2 is known to regulate many different biological functions, including neurogenesis, smooth muscle contractility, angiogenesis and circadian rhythm. In serving the latter role, prokineticin 2 functions as an output molecule from the suprachiasmatic nucleus (SCN) of the hypothalamus, that transmits behavioral rhythms, but may also function locally within the SCN to synchronize output. Prokineticin 2 expression is induced by CLOCK and BMAL1 heterodimers and light, and is inhibited by ...
| Reactivity: | Human, Mouse, Rat, Bovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
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| Reactivity: | Human |
| Sensitivity: | 0.19 ng/mL |
| Assay Range: | 0.31 - 20 ng/mL |
| Applications: | ELISA |
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| Reactivity: | Mouse |
| Sensitivity: | 0.09 ng/mL |
| Assay Range: | 0.16 - 10 ng/mL |
| Applications: | ELISA |
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| Reactivity: | Rat |
| Sensitivity: | 0.19 ng/mL |
| Assay Range: | 0.31 - 20 ng/mL |
| Applications: | ELISA |
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| Reactivity: | Human |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
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Potent prokineticin (PK) 1 and 2 receptor antagonist; antitumor; BBB penetrant
| Alternate Names: | PROK2 Antagonist,Bv8 Antagonist,PK2 Antagonist,Prokineticin 2 Antagonist |
| Chemical Name: | (3R)-N-[(9-Chloro-3,4-dihydro-2H-1,5-benzodioxepin-7-yl)methyl]-1-[(4-fluoro-3-methoxyphenyl)methyl]-N-(2-methylpropyl)-3-pyrrolidinecarboxamide hydrochloride |
| Purity: | ≥98% |
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