3 results for "PTGER4/EP4" in Products

PTGER4/EP4 Products

Prostaglandin E receptor EP4 is a Prostanoid Receptor with a relaxing effect on smooth muscle. It may play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. EP4 has been reported to be expressed in blood, colon, immune tissue, intestine, kidney, lung, ovary, skin, and uterus. ESTs have been isolated from a wide range of human tissue libraries.

Selective EP4 receptor antagonist

Chemical Name: N-[[4'-[[3-Butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfonyl]-3-methyl-2-thiophenecarboxamide
Purity: ≥98%
Selective EP4 receptor antagonist
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High affinity and selective EP4 antagonist

Chemical Name: 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid
Purity: ≥98%
High affinity and selective EP4 antagonist
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High affinity and selective EP4 antagonist

Alternate Names: PGN 1531
Chemical Name: 4-[[4-(5-Methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamide hydrochloride
Purity: ≥98%
High affinity and selective EP4 antagonist
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