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293 results for "R-Spondin 3" in Products
R-Spondin 3 Products
R-Spondin 3 (RSPO3; Cristin 1) is a secreted Wnt regulating protein that is critical for development of the placental labyrinthine layer. It is expressed in the roof plate, tail, somites, otic vesicles, cephalic mesoderm, truncus arteriosus, atrioventricular canal of the developing heart, and strongly but transiently in developing limbs. R-Spondins regulate Wnt/β-catenin by competing with the Wnt antagonist DKK-1 for binding to the Wnt co-receptors LRP-6 and Kremen, reducing their DKK-1-mediated internalization. Reports differ on whether R-Spondins bind LRP-6 directly.
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | Q9BXY4 |
| Applications: | Bioactivity |
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| Reactivity: | Mouse |
| Source: | CHO |
| Accession #: | Q2TJ95 |
| Applications: | Bioactivity |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3D5 |
| Applications: | IHC |
![Immunohistochemistry: R-Spondin 3 Antibody (OTI3D5) [NBP2-45637]](https://resources.rndsystems.com/images/products/R-Spondin-3-Antibody-3D5-Immunohistochemistry-NBP2-45637-img0015.jpg "Immunohistochemistry: R-Spondin 3 Antibody (OTI3D5) [NBP2-45637]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3D5 |
| Applications: | IHC |
![Immunohistochemistry: R-Spondin 3 Antibody (OTI3D5) - Azide and BSA Free [NBP2-73949]](https://resources.rndsystems.com/images/products/R-Spondin-3-Antibody-OTI3D5-Azide-and-BSA-Free-Immunohistochemistry-NBP2-73949-img0015.jpg "Immunohistochemistry: R-Spondin 3 Antibody (OTI3D5) - Azide and BSA Free [NBP2-73949]")
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| Reactivity: | Mouse |
| Assay Range: | 9.38-600 pg/mL |
| Applications: | ELISA |
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| Reactivity: | Human, Mouse |
| Details: | Rat IgG2B Monoclonal Clone #400403 |
| Applications: | WB |
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| Reactivity: | Human |
| Assay Range: | 15.6-1000 pg/mL |
| Applications: | ELISA |
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| Reactivity: | Cynomolgus Monkey |
| Source: | HEK293 |
| Accession #: | XP_005551811.1 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Source: | CHO |
| Accession #: | Q9BXY4.1 |
| Applications: | Bioactivity |
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| Reactivity: | Mouse |
| Source: | CHO |
| Accession #: | Q2TJ95.2 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Source: | E. coli |
| Accession #: | Q9BXY4.1 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | B/N |
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| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #400404 |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1028220 |
| Applications: | ELISA |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1028231 |
| Applications: | ELISA |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: R-Spondin 3 Antibody [NBP1-82234]](https://resources.rndsystems.com/images/products/R-Spondin-3-Antibody-Immunohistochemistry-Paraffin-NBP1-82234-img0008.jpg "Immunohistochemistry-Paraffin: R-Spondin 3 Antibody [NBP1-82234]")
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| Reactivity: | Human |
| Applications: |
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| Reactivity: | Cynomolgus Monkey |
| Applications: |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: R-Spondin 3 AntibodyBSA Free [NBP2-81849]](https://resources.rndsystems.com/images/products/R-Spondin-3-Antibody-Western-Blot-NBP2-81849-img0002.jpg "Western Blot: R-Spondin 3 AntibodyBSA Free [NBP2-81849]")
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| Reactivity: | Human, Mouse |
| Details: | Rat IgG2B Monoclonal Clone #400403 |
| Applications: | WB |
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| Reactivity: | Human, Mouse |
| Details: | Rat IgG2B Monoclonal Clone #400403 |
| Applications: | WB |
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| Reactivity: | Human, Mouse |
| Details: | Rat IgG2B Monoclonal Clone #400403 |
| Applications: | WB |
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| Reactivity: | Human, Mouse |
| Details: | Rat IgG2B Monoclonal Clone #400403 |
| Applications: | WB |
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| Reactivity: | Human, Mouse |
| Details: | Rat IgG2B Monoclonal Clone #400403 |
| Applications: | WB |
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