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1 result for "SCNN1D" in Products
SCNN1D Products
SCNN1D is a subunit of the epithelial sodium channel (ENaC). ENaC has high sodium selectivity, low conductance, and amiloride sensitivity. The epithelial Na(+) channel (ENaC) regulates Na(+) homeostasis in cells and across epithelia; in the kidney, lung and colon it plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium re-uptake in the distal nephron of the kidney, thus regulating blood pressure. Four homologous ENaC subunits ...
NCX inhibitor, Deg/ENaC channel blocker; amiloride (Cat. No. 0890) derivative
| Chemical Name: | N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride |
| Purity: | ≥98% |
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