SOX1: Products

Members of the large SOX family of transcription factors are widely conserved and at least 20 are found in mammals. Structurally SOX proteins exhibit a high mobility group (HMG) motif that binds the DNA minor groove.

SOX1 (SRY-related HMG box 1) is a 39 kDa transcription factor that belongs to the SRY family of HMG box proteins. Group B contains SOX1 along with SOX2, SOX3, SOX14, and SOX21; each of these factors share greater than 90% homology in their respective HMG box region. SOX1 maintains neural cells in an undifferentiated state and has been used as a marker for neural stem cells. Human and mouse SOX1 share 97% amino acid sequence identity.

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Human/Mouse/Rat SOX1 Antibody 

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ICC/IF, Simple Western, WB
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