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2 results for "SREBP Inhibitors Small Molecules and Peptides" in Products
SREBP Inhibitors Small Molecules and Peptides
SREBPs (sterol regulatory element-binding proteins) are membrane bound transcription factors that are essential in the regulation of cholesterol, fatty acid and triglyceride biosynthesis. There are two SREBP genes in mammals, SREBP-1, which is most abundant in the liver and adrenal glands, and SREBP-2, which is ubiquitously expressed. In addition, SREBP-1 encodes two different isoforms of the protein, SREBP-1a and SREBP-1c, expression of which is dependent on the promoter. The proteins form a ...
Cell permeable inhibitor of SREBP activation
| Chemical Name: | 4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide |
| Purity: | ≥97% |
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Competitive inhibitor of SREBP site 1 protease
| Chemical Name: | 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide dihydrochloride |
| Purity: | ≥97% |
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