2 results for "Translocator Protein Ligands" in Products

Translocator Protein Ligands

The translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor or PBR, is an 18 KDa protein that is ubiquitously expressed and localized to the outer mitochondrial membrane in eukaryotes. It was first identified in 1977 as a secondary binding site for benzodiazepines, but its function remains obscure. Crystal and NMR structures have revealed that the protein has some characteristics of both a transporter and a G-protein coupled receptor. Cholesterol, porphyrins and ...

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Ligand of the translocator protein (TSPO); also GABAA receptor potentiator

Chemical Name: 6-Chloro-2-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine hydrochloride
Purity: ≥98%
Ligand of the translocator protein (TSPO); also GABAA receptor potentiator
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Selective TSPO ligand

Alternate Names: XBD173
Chemical Name: N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide
Purity: ≥98%
Selective TSPO ligand
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