2 results for "Voltage-gated Potassium Channel Blockers" in Products

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Voltage-gated Potassium Channel Blockers

Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming α-subunits contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.

Terfenadine

Catalog #: 3948
(1)
Citations (17)
Product Documents

H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Chemical Name: α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Purity: ≥98%
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Astemizole

Catalog #: 3489
(1)
Citations (13)
Product Documents

Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker

Alternate Names: Hismanal
Chemical Name: 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
Purity: ≥98%
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker
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