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3 results for "Wee1" in Products
Wee1 Products
Wee1 encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
Potent and selective inhibitor of Chk1 and Wee1
| Chemical Name: | 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione |
| Purity: | ≥98% |
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Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
| Chemical Name: | 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride |
| Purity: | ≥98% |
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Potent and selective Wee1 inhibitor
| Alternate Names: | AZD 1775,MK 1775 |
| Chemical Name: | 1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one |
| Purity: | ≥98% |
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