Bcl-10 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-76882

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Bcl-10 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to amino acids near the amino terminus of human Bcl10. The immunogen is located within the first 50 amino acids of Bcl-10. Amino Acid Squence: APSLTEEDLTEVKKDC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit Bcl-10 Antibody - BSA Free (NBP1-76882) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Bcl-10 Antibody - BSA Free

Western Blot: Bcl-10 AntibodyBSA Free [NBP1-76882]

Western Blot: Bcl-10 AntibodyBSA Free [NBP1-76882]

Western Blot: Bcl-10 Antibody [NBP1-76882] - Raji whole cell lysate in the absence (A) or presence (B) of peptide (2161P) with Bcl-10 antibody at 1:500 dilution.
Bcl-10 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Bcl-10 Antibody - BSA Free [NBP1-76882] -

Immunocytochemistry/ Immunofluorescence: Bcl-10 Antibody - BSA Free [NBP1-76882] - Immunofluorescence of Bcl-10 in Raji cells with Bcl-10 antibody at 10 u/mL.
Bcl-10 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Bcl-10 Antibody - BSA Free [NBP1-76882] -

Immunocytochemistry/ Immunofluorescence: Bcl-10 Antibody - BSA Free [NBP1-76882] - Immunocytochemistry of Bcl10 in Raji cells with Bcl10 antibody at 1 ug/mL.

Applications for Bcl-10 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1-10 ug/ml

Western Blot

0.5 ug/ml
Application Notes
An approximately 31 kDa band can be detected in Western Blot.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Bcl-10

Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP. Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF-kappaB activation. Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing and induces apoptosis through caspase-9 activation. Bcl10 exhibits a variety of mutations in MALT lymphomas and in B and T cell lineage lymphomas indicating that it may be commonly involved in the pathogenesis of human malignancy. Bcl10 is expressed in many human and murine tissues and cell lines.

Long Name

B Cell Lymphoma/Leukemia 10

Alternate Names

Bcl10, c-E10, CARMEN, CIPER, CLAP, mE10

Gene Symbol

BCL10

UniProt

AF134395 (Human)

Additional Bcl-10 Products

Product Documents for Bcl-10 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Bcl-10 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for Bcl-10 Antibody - BSA Free

There are currently no reviews for this product. Be the first to review Bcl-10 Antibody - BSA Free and earn rewards!

Have you used Bcl-10 Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies