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Recombinant Mammal CCL22/MDC Protein

Name: Recombinant Mammal CCL22/MDC Protein
Brand: Novus Biologicals
SKU: NBP3-57535
Price: 449 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-57535

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Product Specifications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Applications

Western Blot, ELISA, Cell Culture

View all CCL22/MDC Proteins and Enzymes »

Product Specifications

Description

A recombinant protein corresponding to 72 aa of Mammal CCL22/MDC.

Source: Yeast

Amino Acid Sequence: TEAGPYGANV EDSICCRDYI RHPLPLRLVK YYYWTSESCR RPGVVLLTVR DREICADPRL PWVKKILQRL DQ (72)

Stable for up to 12 months from date of receipt at -20C. Stable for 3 months when stored in working aliquots with a carrier protein at -20C. Avoid repeated freeze/thaw cycles.

Purity

>98%, by SDS-PAGE

Endotoxin Level

No affinity tags & naturally endotoxin-free

Predicted Molecular Mass

8.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Enzyme-linked Immunosorbent Spot (ELISPOT)
ELISA Standard (Matched Pair) (ELISA(Sta))

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation, and Storage

NBP3-57535

Formulation	Lyophilized in 1-5X PBS containing 10% Trehalose
Preservative	10% Trehalose
Concentration	Lyoph
Reconstitution	Reconstitute in sterile PBS with at least 0.1% carrier protein
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: CCL22/MDC

Chemokines are a large family of small secreted proteins that regulate migration of white blood cells. Based on the arrangement of the first two of the four conserved cysteine residues, chemokines are classified into four subfamilies, CXC, CC, C and recently identified CX3C (1). The CC chemokines, in which the first 2 cysteines are adjacent, usually act on monocytes, T lymphocytes, and, in some cases, eosinophils, basophils, or mast cells. The CC subfamily proteins are 70 to 100 amino acids long, have 25 to 75% identity with each other, and include novel member of the CC chemokine subfamily, designated ABCD1 (SCYA22). The SCYA22 protein shares 28 to 34% identity with other CC chemokines and contains the characteristic 4-cysteine motif and 9 other highly conserved residues (2). The activated T cell-attracting CC chemokine CCL22 is expressed by stimulated B cells and mature dendritic cells (DC). Both identical and distinct proteins contribute to expression of CCL22 in DC and B cells (3).

Alternate Names

ABCD-1, MDC, STCP-1

Gene Symbol

CCL22

Additional CCL22/MDC Products

Product Documents for Recombinant Mammal CCL22/MDC Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Mammal CCL22/MDC Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.