Complement C4 Antibody (23GB4985)

Novus Biologicals | Catalog # NBP3-50420

Novus Biologicals
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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB4985
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Product Specifications

Immunogen

A synthesized peptide derived from human Complement C4 (Uniprot: P0C0L4)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for Complement C4 Antibody (23GB4985)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

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Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Complement C4

C4 consists of three polypeptide chains (alpha, molecular weight 95 kDa, beta, molecular weight 75 kDa and gamma, molecular weight 33 kDa) and is usually present in serum at 200-600mg/L. It is a protein of the classical complement pathway. When activated by C1s, a peptide C4a is released and the generated C4b binds C2 which is in turn cleaved by C1s to produce the classical pathway C3 convertase, namely C4b2a. C4b also has opsonin activity and binds to macrophages and neutrophils via their CR1 receptor.

Alternate Names

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4, complement component 4A (Rodgers blood group), RG

Gene Symbol

C4A

Additional Complement C4 Products

Product Documents for Complement C4 Antibody (23GB4985)

Certificate of Analysis

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Product Specific Notices for Complement C4 Antibody (23GB4985)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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