Human 5-HT7 APC‑conjugated Antibody

R&D Systems | Catalog # FAB10325A

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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 1015322
View all 5-HT7 Primary Antibodies »

Product Specifications

Immunogen

 Synthetic peptide containing human 5-HTR7
Accession # P34969

Specificity

Detects human 5-HTR7 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human 5-HT7 APC‑conjugated Antibody

5-HT7 Antibody (1015322) [Allophycocyanin]

Detection of 5-HT7 in 5-HT7 HEK293/eGFP transfecants vs Irrelevant HEK293/eGFP transfecants by Flow Cytometry

5-HT7 HEK293/eGFP transfecants (A) vs Irrelevant HEK293/eGFP transfecants (B) were stained with Mouse Anti-Human 5-HT7 APC‑conjugated Monoclonal Antibody (Catalog # FAB10325A). View our protocol for Staining Membrane-associated Proteins.

Applications for Human 5-HT7 APC‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Transfectants (see below)

Spectra Viewer

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

Supplied in a saline solution containing Tris, NaCl and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: 5-HT7

HTR2B is a G-protein coupled receptor for serotonin. The 5HT2 receptors mediate many of the central and peripheral physiologic functions of serotonin. 5HT2B plays a role in the regulation of dopamine and serotonin release, serotonin uptake and in the regulation of extracellular dopamine and serotonin levels.  It also plays a role in pulmonary vasoconstriction and regulating cardiac structure and functions.  5HT2B receptors were shown to be expressed in human failing heart and have been strongly implicated in drug induced valvular heart disease.

Long Name

5-Hydroxytryptamine Receptor 7

Alternate Names

5-HT-X, 5HT7, HTR7

Entrez Gene IDs

3363 (Human); 15566 (Mouse); 65032 (Rat)

Gene Symbol

HTR7

UniProt

P34969

Additional 5-HT7 Products

Product Documents for Human 5-HT7 APC‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human 5-HT7 APC‑conjugated Antibody

For research use only

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