Human CLEC14A APC‑conjugated Antibody

R&D Systems | Catalog # FAB7436A

R&D Systems
Discontinued Product
FAB7436A has been discontinued. View all CLEC14A products.

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 743940
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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CLEC14A
Glu22-Ala397
Accession # Q86T13

Specificity

Detects human CLEC14A in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human CLEC14A APC‑conjugated Antibody

Detection of CLEC14A antibody in HUVEC Human Cells antibody by Flow Cytometry.

Detection of CLEC14A in HUVEC Human Cells by Flow Cytometry.

HUVEC human umbilical vein endothelial cells was stained with Mouse Anti-Human CLEC14A APC-conjugated Monoclonal Antibody (Catalog # FAB7436A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CLEC14A APC‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: HUVEC human umbilical vein endothelial cells

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Flow Cytometry Panel Builder

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Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: CLEC14A

CLEC14A (C-type Lectin Domain Family 14 Member A), also known as EGFR5, is a 51 kDa (predicted) member of the C-type lectin domain family of proteins. It is a type I transmembrane protein, apparently expressed in brain and about which little is known. Mature human CLEC14A is 469 amino acids (aa) in length. It contains a 376 aa extracellular region (aa 22-397) and a 72 aa cytoplasmic domain. The extracellular region shows one C-type lectin like domain (aa 32-175) and an EGF-like region (aa 245-287). Over aa 22-397, human CLEC14A shares 66% and 81% aa identity with mouse and canine CLEC14A, respectively.

Long Name

C-type Lectin Domain Family 14, Member A

Alternate Names

CEG1, EGF R5

Entrez Gene IDs

161198 (Human); 66864 (Mouse); 314148 (Rat)

Gene Symbol

CLEC14A

UniProt

Additional CLEC14A Products

Product Documents for Human CLEC14A APC‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human CLEC14A APC‑conjugated Antibody

For research use only

Related Research Areas

Citations for Human CLEC14A APC‑conjugated Antibody

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