Home / DCIR/CLEC4A / Human DCIR/CLEC4A PE-conjugated Antibody

Human DCIR/CLEC4A PE-conjugated Antibody

Catalog #: FAB1748P
4 Citations Datasheet / COA / SDS
Clone 216110 was used by HLDA to establish CD designation

Discontinued Product

FAB1748P has been discontinued.
View all DCIR/CLEC4A products.
Detection of DCIR/CLEC4A in Human Blood Neutrophils by Flow Cytometry.
1 Image
Product Details
Citations (4)
FAQs
Reviews
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human DCIR/CLEC4A PE-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human DCIR/CLEC4A in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG1 Clone # 216110
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human DCIR isoform 1
Gln70-Leu237
Accession # Q9UMR7
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of DCIR/CLEC4A antibody in Human Blood Neutrophils antibody by Flow Cytometry. View Larger

Detection of DCIR/CLEC4A in Human Blood Neutrophils by Flow Cytometry. Human peripheral blood neutrophils were stained with Mouse Anti-Human DCIR/CLEC4A PE-conjugated Monoclonal Antibody (Catalog # FAB1748P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: DCIR/CLEC4A

DCIR, also known as Lectin-Like Immunoreceptor (LLIR), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM) in its cytoplasmic domain. Besides dendritic cells, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.

Long Name
Dendritic Cell Immunoreceptor
Entrez Gene IDs
50856 (Human); 26888 (Mouse)
Alternate Names
CD367; CLEC4A; CLECSF6; CLECSF6C-type lectin superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; DCIR; DCIRLLIR; DDB27; DDB27C-type lectin DDB27; Dendritic cell immunoreceptor; Lectin-like immunoreceptor; LLIR

Product Datasheets

You must select a language.

x
Product Datasheet
COA
SDS

Citations for Human DCIR/CLEC4A PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
Filter your results:

Filter by:

  1. Agonistic anti-DCIR antibody inhibits ITAM-mediated inflammatory signaling and promotes immune resolution
    Authors: Chen, L;Patil, S;Barbon, J;Waire, J;Laroux, FS;McCarthy, D;Pratibha, M;Zhong, S;Dong, F;Orsi, K;Nguyen, G;Yang, Y;Crosbie, N;Dominguez, E;Deora, A;Veldman, G;Westmoreland, SV;Jin, L;Radstake, T;White, K;Wei, HJ;
    JCI insight
    Species: Human, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Identification of HIV transmitting CD11c+ human epidermal dendritic cells
    Authors: KM Bertram, RA Botting, H Baharlou, JW Rhodes, H Rana, JD Graham, E Patrick, J Fletcher, TM Plasto, NR Truong, C Royle, CM Doyle, O Tong, N Nasr, L Barnouti, MP Kohout, AJ Brooks, MP Wines, P Haertsch, J Lim, MP Gosselink, G Ctercteko, JD Estes, MJ Churchill, PU Cameron, E Hunter, MA Haniffa, AL Cunningham, AN Harman
    Nat Commun, 2019-06-21;10(1):2759.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes
    Authors: RA Botting, KM Bertram, H Baharlou, KJ Sandgren, J Fletcher, JW Rhodes, H Rana, TM Plasto, XM Wang, JJ Lim, L Barnouti, MP Kohout, T Papadopoul, S Merten, N Olbourne, AL Cunningham, M Haniffa, AN Harman
    J. Leukoc. Biol, 2017-03-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
    Authors: Llinas L, Lazaro A, de Salort J, Matesanz-Isabel J, Sintes J, Engel P
    Immunol. Lett., 2010-10-15;134(2):113-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Human DCIR/CLEC4A PE-conjugated Antibody

There are currently no reviews for this product. Be the first to review Human DCIR/CLEC4A PE-conjugated Antibody and earn rewards!

Have you used Human DCIR/CLEC4A PE-conjugated Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review