Human GATA-4 Alexa Fluor® 700-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: GATA-4

GATA-4 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-4 interacts with other transcription factors such as NKX2.5, and myocyte enhancer factor 2 to regulate cardiac myocyte-specific gene expression. GATA-4 contains 2 zinc finger-binding domains and migrates at 56 kDa in SDS-PAGE gels. Human GATA-4 share 93%, 93% and 92% amino acid sequence identity with porcine, rat and mouse GATA-4, respectively.

Product Datasheets

Related Research Areas

• Cardiac Stem Cell Markers
• Definitive Endoderm Markers
• Early Endodermal Lineage Markers
• GATA Transcription Factors
• Hepatic Endoderm
• Hepatic Endoderm Cell Markers
• Mesenchymal Stem Cell Transcription Factors
• Primitive Endoderm Markers
• Transcription Factors in the Akt Pathway
• Transcription Regulators in VSMC