Human GluR3 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB11329U Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11329U-100UG

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Human GluR3 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human GluR3 in direct ELISA.
Source
Monoclonal Mouse IgG2b Clone # 1059821
Purification
Protein A or G purified
Immunogen
Synthetic Peptide
Accession # P42263
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GluR3

GluR3 is a receptor for glutamate. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiological processes. This gene belongs to a family of AMPA receptors.  GluR3 is a gene product of the GRIA3 gene and its pre-mRNA is subject to RNA editing. In humans, 80-90% of GRIA3 transcripts are edited. This allows sustained response to rapid stimuli. There is a tentative link between defective GRIA3 variants and a highly elevated risk of schizophrenia.

Long Name
Glutamate Receptor 3
Entrez Gene IDs
2892 (Human); 53623 (Mouse); 29628 (Rat)
Alternate Names
AMPA 3; AMPA3; AMPA-selective glutamate receptor 3; GluA3; GluR3; GluR-3; GLURC; GLUR-C; GLUR-K3; glutamate receptor C; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; GRIA3

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