Human GluR3 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB11329V Datasheet / COA / SDS

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FAB11329V-100UG

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Human GluR3 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human GluR3 in direct ELISA.

Source

Monoclonal Mouse IgG2b Clone # 1059821

Purification

Protein A or G purified

Immunogen

Synthetic Peptide
Accession # P42263

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GluR3

GluR3 is a receptor for glutamate. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiological processes. This gene belongs to a family of AMPA receptors. GluR3 is a gene product of the GRIA3 gene and its pre-mRNA is subject to RNA editing. In humans, 80-90% of GRIA3 transcripts are edited. This allows sustained response to rapid stimuli. There is a tentative link between defective GRIA3 variants and a highly elevated risk of schizophrenia.

Long Name

Glutamate Receptor 3

Entrez Gene IDs

2892 (Human); 53623 (Mouse); 29628 (Rat)

Alternate Names

AMPA 3; AMPA3; AMPA-selective glutamate receptor 3; GluA3; GluR3; GluR-3; GLURC; GLUR-C; GLUR-K3; glutamate receptor C; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; GRIA3