Human/Mouse JunD Alexa Fluor® 350-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: JunD

JunD is a member of the Jun family of nuclear transcription factors. It dimerizes with other Jun or FOS family members to form the AP1 transcription factor. Unlike c-Jun or JunB, JunD antagonizes Ras transformation and accumulates as cells enter quiescence. JunD has two isoforms full length at 347 amino acids (aa), the other 303 aa which initiates translation at aa 44. Over the sequence used as an immunogen, human JunD shares 80% aa identity with mouse and rat JunD. The activation of JunD appears to reduce the proliferation of breast cancer cells.

Product Datasheets

Related Research Areas

• Apoptosis Transcription Factors and Regulators
• Basic Leucine Zipper (bZIP) Transcription Factors
• Cancer Biomarkers
• Cancer Stem Cell Transcription Factors
• C-type Lectin Receptors
• IL-1 Family
• IL-17 Family
• NOD-like Receptors and the Inflammasome
• Toll-Like Receptors
• VEGF Family
• Wnt Intracellular Signaling