Human Rab13 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB8305S Datasheet / COA / SDS

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FAB8305S-100UG

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Human Rab13 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Rab13 in direct ELISA and Western Blot.

Source

Monoclonal Mouse IgG2a Clone # 863028

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Rab13
Lys94-Thr191
Accession # P51153

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Knockout Validated

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Rab13

Ras-related protein Rab13 is a 23 kDa member of the Rab family of small GTPases. With more than 40 family members, Rab proteins are regulators of vesicular transport, and their number reflects the complexity of vesicle trafficking. Rab13 is detected in endothelial cells and a variety of epithelia, including intestine, lung, kidney and liver. Rab13 may participate in the assembly and activity of tight junctions, as it colocalizes with the marker ZO-1 in polarized epithelial cells. In addition, insulin promotes GTP loading of Rab13, potentially regulating GLUT4 translocation in skeletal muscle cells. Human Rab13 is 203 amino acids (aa) in length, with residues 201-203 removed in its mature form. Over aa 94-191, human Rab13 shares 89 and 90% identity with mouse and rat Rab13, respectively.

Long Name

RAs Genes from Brain Protein 13

Entrez Gene IDs

5872 (Human); 68328 (Mouse); 81756 (Rat)

Alternate Names

Cell growth-inhibiting gene 4 protein; growth-inhibiting gene 4 protein; Rab13; RAB13, member RAS oncogene family; RAS-associated protein RAB13; ras-related protein Rab-13