Human/Rat/Chicken Laminin S Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB2066V Datasheet / COA / SDS

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FAB2066V-100UG

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Human/Rat/Chicken Laminin S Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human, Rat, Chicken

Specificity

Detects human, rat, and chicken Laminin S in Western blots.

Source

Monoclonal Mouse IgG1 Clone # C4

Purification

Protein A or G purified

Immunogen

Bovine anterior lens capsule

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Laminin S

Laminins are heterotrimeric, noncollagenous glycoproteins composed of alpha, beta and gamma chains. Through interactions with integrins, dystroglycan and other receptors, laminins critically contribute to cell differentation, cell shape and migration and maintenance of tissue phenotypes and survival (1). Laminin S, also known as laminin beta 2, is a subunit of laminin-3 (S-laminin), laminin-4 (S-merosin) and laminin-7 (KS-laminin). It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle.

Long Name

Laminin, beta 2

Entrez Gene IDs

3913 (Human)

Alternate Names

LAMB2; Laminin B1s chain; Laminin beta 2; Laminin S; laminin subunit beta-2; laminin, beta 2 (laminin S); Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; LAMSLaminin-9 subunit beta; S-LAM beta; S-laminin subunit beta