Human SCL/Tal1 Alexa Fluor® 350-conjugated Antibody

Catalog #: AF3360U Datasheet / COA / SDS

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AF3360U-100UG

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All SCL/Tal1 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human SCL/Tal1 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human SCL in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human SCL
Arg199-Gly266
Accession # P17542

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: SCL/Tal1

SCL, also known as TAL-1 (T-cell Acute Lymphocytic Leukemia-1 protein), is a 40 kDa basic helix-loop-helix transcription factor. It regulates hematopoiesis, angiogenesis and erythrocyte maturation. Activation of SCL by chromosomal translocation may be a cause of some T-cell acute lymphoblastic leukemia. Two alternative splice variants lacking the first 25 or 175 amino acid residues also exist. Human and mouse SCL share 93% amino acid sequence identity.

Long Name

Stem Cell Leukemia/T-cell Acute Lymphocytic Leukemia 1

Entrez Gene IDs

6886 (Human)

Alternate Names

BHLHA17; bHLHa17tal-1; Class A basic helix-loop-helix protein 17; SCL; SCLT-cell acute lymphocytic leukemia protein 1; Stem Cell Protein; Tal1; TAL-1; T-cell acute lymphocytic leukemia 1; T-cell leukemia/lymphoma protein 5; TCL5; TCL5tal-1 product