Ly49C Antibody (14B11) - Azide and BSA Free

Novus Biologicals | Catalog # NBP1-28082

Novus Biologicals
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Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Golden Syrian Hamster IgG1 Clone # 14B11

Format

Azide and BSA Free
View all Ly49C Primary Antibodies »

Product Specifications

Immunogen

IL-2 activated natural killed (A-LAK) cells from C57BL/6 mice

Specificity

An epitope common to the Ly49C, Ly49F, Ly49H and Ly49I allelic/splice variants

Clonality

Monoclonal

Host

Golden Syrian Hamster

Isotype

IgG1

Scientific Data Images for Ly49C Antibody (14B11) - Azide and BSA Free

Flow Cytometry: Ly49C Antibody (14B11) - Azide and BSA Free [NBP1-28082]

Flow Cytometry: Ly49C Antibody (14B11) - Azide and BSA Free [NBP1-28082]

Flow Cytometry: Ly49C Antibody (14B11) [NBP1-28082] - Analysis of splenocytes by multiple staining.

Applications for Ly49C Antibody (14B11) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

<= 1 ug/10^6 cells

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.1M BBS (pH 8.2)

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Ly49C

The monoclonal antibody 14B11 reacts with murine Ly49C, Ly49F, Ly49H and Ly49I, members of the lectin-like homodimeric Ly49 family of cell surface receptors. (1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. (2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. The 14B11 antibody stains approx. 90% of NK1.1+CD3- splenocytes, and approx. 6% of CD8+ spleen cells from C57BL/6 mice. (1) The antibody also stains 30-80% of NK1.1+CD3- splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J).

Alternate Names

5000000, Cmv1, Killer cell lectin like receptor 3, Killer cell lectin like receptor 6, Killer cell lectin like receptor 8, Killer cell lectin like receptor 9, Klra3, Klra6, Klra8, Klra9, Ly49 C antigen, Ly49 F antigen, Ly49 H antigen, Ly49 I antigen, Lymphocyte antigen 49C, Lymphocyte antigen 49F, Lymphocyte antigen 49H, Lymphocyte antigen 49I, T cell surface glycoprotein Ly 49C, T cell surface glycoprotein Ly 49F, T cell surface glycoprotein Ly 49H, T cell surface glycoprotein Ly 49I

Additional Ly49C Products

Product Documents for Ly49C Antibody (14B11) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for Ly49C Antibody (14B11) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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