MCG10 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-76729

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Bovine (100%), Mouse (100%). Backed by our 100% Guarantee.

Applications

Validated:

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Cited:

Westen Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all MCG10 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human MCG10. The immunogen is located within the last 50 amino acids of MCG10.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MCG10 Antibody - BSA Free

Western Blot: MCG10 AntibodyBSA Free [NBP1-76729]

Western Blot: MCG10 AntibodyBSA Free [NBP1-76729]

Western Blot: MCG10 Antibody [NBP1-76729] - HeLa cell lysate with MCG10 antibody at (A) 0.5, (B) 1 and (C) 2 u/mL.
MCG10 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody - BSA Free [NBP1-76729] -

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody - BSA Free [NBP1-76729] - Immunocytochemistry of MCG10 in HeLa cells with MCG10 antibody at 1 u/mL.
MCG10 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody - BSA Free [NBP1-76729] -

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody - BSA Free [NBP1-76729] - Immunofluorescence of MCG10 in Hela cells with MCG10 antibody at 20 ug/mL.

Applications for MCG10 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1-20 ug/ml

Western Blot

0.5 - 2 ug/mL

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MCG10

MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.

Alternate Names

Alpha-CP4, alphaCP-4 protein, CBP, LIP4, LYST-interacting protein, MCG10, poly(rC) binding protein 4, poly(rC)-binding protein 4, RNA binding protein MCG10

Gene Symbol

PCBP4

UniProt

EAW65166 (Human)

Additional MCG10 Products

Product Documents for MCG10 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for MCG10 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for MCG10 Antibody - BSA Free

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Protocols

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