Mouse MUCDHL Alexa Fluor® 647-conjugated Antibody

Catalog #: AF4159R Datasheet / COA / SDS

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AF4159R-100UG

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Mouse MUCDHL Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse MUCDHL in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human MUCDHL is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse MUCDHL
Gln29-Ala479
Accession # NP_082345

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilution of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MUCDHL

Mucin and cadherin-like protein (MUCDHL), also known as μ-protocadherin, is a 100 kDa type I transmembrane protein belonging to the protocadherin family of cell adhesion molecules. It is found apically on the brush border of renal proximal tubule epithelial cells. The extracellular domain of mature mouse MUCDHL contains four cadherin domains plus three repeat regions that constitute a mucin stalk (aa 541‑614). At least one splice variant exists in mouse that shows a deletion of aa’s 459‑620. Over aa’s 29‑479, mouse MUCDHL shares 63% and 79% aa identity with human and rat MUCDHL, respectively.

Long Name

Mucin And Cadherin-like

Entrez Gene IDs

53841 (Human); 72040 (Mouse); 171554 (Rat)

Alternate Names

cadherin-related family member 5; CDHR5; FLJ20219; MUCDHL; MUCDHLmucin-like protocadherin; Mucin and cadherin-like protein; mucin and cadherin-like; MUPCDH; MU-PCDH; mu-protocadherin