SM 102

Tocris Bioscience | Catalog # 8909

Cationic ionizable lipid
Tocris Bioscience
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Key Product Details

Description

Cationic ionizable lipid

Product Description

SM 102 is an ionizable cationic lipid (pKa = 6.68) used in the formulation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Administration of LNPs containing SM 102 induces hepatic luciferase expression in mice. SM 102 is commonly formulated with cholesterol (Cat. No. 7945), DSPC (Cat. No. 7943), and DMG-PEG 2000 (Cat. No. 7944).

This product is supplied pre-dissolved in anhydrous ethanol, 100mg/mL

For more information on LNPs and available components see our Lipid Nanoparticles page.

Product Specifications for SM 102

Molecular Weight

710.17

Formula

C44H87NO5

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]octanoate

CAS Number

2089251-47-6

PubChem ID

126697616

InChI Key

BGNVBNJYBVCBJH-UHFFFAOYSA-N

SMILES

O=C(OCCCCCCCCCCC)CCCCCN(CCO)CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solubility Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 100mg/mL)

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for SM 102

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SM 102

For research use only

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