SM 102
Tocris Bioscience | Catalog # 8909
Product Description
SM 102 is an ionizable cationic lipid (pKa = 6.68) used in the formulation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Administration of LNPs containing SM 102 induces hepatic luciferase expression in mice. SM 102 is commonly formulated with cholesterol (Cat. No. 7945), DSPC (Cat. No. 7943), and DMG-PEG 2000 (Cat. No. 7944).
This product is supplied pre-dissolved in anhydrous ethanol, 100mg/mL
For more information on LNPs and available components see our Lipid Nanoparticles page.
Product Specifications for SM 102
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 100mg/mL) |
Calculators
Background References
References are publications that support the biological activity of the product.
- Sabnis A novel amino lipid series for mRNA delivery: improved endosomal escape and sustained pharmacology and safety in non-human primates. Mol.Ther. 2018 PMID: 29653760
- Hassett Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines. Mol Ther Nucleic Acids 2019 PMID: 30785039
Product Documents for SM 102
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for SM 102
For research use only
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