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4 results for "Additional p53-related Compounds Small Molecules and Peptides" in 产品
Additional p53-related Compounds Small Molecules and Peptides
p53 is well known for its key role as a tumor suppressor protein. It is 393 amino acids (aa) in length with a predicted molecular weight of 44 kDa. It belongs to the p53 family that also includes p63 and p73. Structurally, p53 is characterized by an N-terminal transactivation domain, central DNA-binding and oligomerization domains, and a C-termina...
Restores mutant p53 activity
| Alternate Names: | APR-246 |
| Chemical Name: | 2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one |
| Purity: | ≥98% |
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Restores mutant p53 activity; proapoptotic
| Chemical Name: | 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione |
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Selective exportin-1 (XPO1/CRM1) inhibitor
| Chemical Name: | (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyridinyl)hydrazide |
| Purity: | ≥98% |
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RNA polymerase I inhibitor; also p53 pathway activator
| Chemical Name: | N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide |
| Purity: | ≥98% |
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